Difference between revisions of "Zi-Ming Zhao"

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<b>Zi-Ming Zhao, Ph.D.</b>
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== Zi-Ming Zhao, Ph.D.==
<img src="https://www.jax.org/-/media/jaxweb/images/research-and-faculty/faculty/zi-ming-zhao.jpg?h=370&w=280&la=en&hash=736408DBDDE92936D6DB6FAB92B86641C451E70B">
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----
Research Scientist
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[[File:Zmz.jpg|right|280px]]
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====Research Scientist====
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====<font color=olive>'''''Understands molecular mechanisms of tumorigenesis and drug resistance using cancer clinical genomic data.'''''</font>====
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[[https://www.jax.org/research-and-faculty/bioinformatics Bioinformatics]],[[https://www.jax.org/research-and-faculty/cancer Cancer]], [[https://www.jax.org/research-and-faculty/computational-biology Computational Biology]], [[https://www.jax.org/research-and-faculty/genetics-and-genomics Genetics And Genomics]], [[https://www.jax.org/research-and-faculty/infectious-disease-research Infectious Disease Research]].
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Contact me:
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Ziming.Zhao@jax.org
 
Ziming.Zhao@jax.org
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860-837-2130
 
860-837-2130
twitter@Dr_ZiMingZhao
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[https://www.jax.org/research-and-faculty/faculty/research-scientists/zi-ming-zhao
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[https://twitter.com/Dr_ZiMingZhao twitter@Dr_ZiMingZhao]
]
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The Jackson Laboratory for Genomic Medicine
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[[https://www.jax.org/research-and-faculty/faculty/research-scientists/zi-ming-zhao VISIT ME AT JAX]]
10 Discovery Drive, Farmington, CT 06032-2352
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===ABOUT ZI-MING ZHAO, Ph.D.===
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I have been interested in understanding genetic origins and molecular evolution of life and human diseases, and finding cures for various human diseases particularly cancer and infectious diseases. My current focus is studying cancer clinical genomics from the perspectives of molecular evolution and population genetics. My goal is to understand the process of tumorigenesis, metastasis and drug resistance, and to identify markers for cancer diagnosis, prognosis, and therapeutics.
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===SELECTED PUBLICATIONS===
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[https://bmcclinpathol.biomedcentral.com/articles/10.1186/s12907-018-0070-7 '''Zhao ZM''', Wang J, Ugwuowo UC, Wang L, and Townsend JP. Primary hepatic neuroendocrine carcinoma: report of two cases. '''''BMC Clinical Pathology'''''. 2018.]
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[https://www.nature.com/articles/s41388-017-0105-z Cannataro VL, Gaffney SG, Stender C, '''Zhao ZM''', Philips M, Greenstein AE, Townsend JP. Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C. '''''Oncogene'''''. 2018]
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[https://academic.oup.com/mbe/article-abstract/34/11/3006/4055061?redirectedFrom=fulltext '''Zhao ZM''', Campbell MC, Li N, Lee DSW, Zhang Z, Townsend JP, Detection of regional variation in selection intensity within protein-coding genes using DNA sequence polymorphism and divergence, '''''Molecular Biology and Evolution'''''. 2017]
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[https://www.ncbi.nlm.nih.gov/pubmed/26858460 '''Zhao ZM''', Zhao B, Bai Y, Iamarino A, Gaffney SG, Schlessinger J, Lifton RP, Rimm DL, Townsend JP. Early and multiple origins of metastatic lineages within primary tumors. '''''Proc Natl Acad Sci U S A'''''. 2016 Feb 23;113(8):2140-5.]
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[https://www.ncbi.nlm.nih.gov/pubmed/27687306 Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, '''Zhao ZM''', Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. '''''Ann Oncol'''''. 2016 Sep 29. pii: mdw436.]
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[[https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/48067188/?sort=date&direction=ascending <font color=blue>VIEW FULL LIST OF PUBLICATIONS</font>]]

Latest revision as of 09:41, 4 June 2018

Zi-Ming Zhao, Ph.D.


Zmz.jpg

Research Scientist

Understands molecular mechanisms of tumorigenesis and drug resistance using cancer clinical genomic data.

[Bioinformatics],[Cancer], [Computational Biology], [Genetics And Genomics], [Infectious Disease Research].

Contact me:

Ziming.Zhao@jax.org

860-837-2130

twitter@Dr_ZiMingZhao

[VISIT ME AT JAX]


ABOUT ZI-MING ZHAO, Ph.D.

I have been interested in understanding genetic origins and molecular evolution of life and human diseases, and finding cures for various human diseases particularly cancer and infectious diseases. My current focus is studying cancer clinical genomics from the perspectives of molecular evolution and population genetics. My goal is to understand the process of tumorigenesis, metastasis and drug resistance, and to identify markers for cancer diagnosis, prognosis, and therapeutics.

SELECTED PUBLICATIONS

Zhao ZM, Wang J, Ugwuowo UC, Wang L, and Townsend JP. Primary hepatic neuroendocrine carcinoma: report of two cases. BMC Clinical Pathology. 2018.

Cannataro VL, Gaffney SG, Stender C, Zhao ZM, Philips M, Greenstein AE, Townsend JP. Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C. Oncogene. 2018

Zhao ZM, Campbell MC, Li N, Lee DSW, Zhang Z, Townsend JP, Detection of regional variation in selection intensity within protein-coding genes using DNA sequence polymorphism and divergence, Molecular Biology and Evolution. 2017

Zhao ZM, Zhao B, Bai Y, Iamarino A, Gaffney SG, Schlessinger J, Lifton RP, Rimm DL, Townsend JP. Early and multiple origins of metastatic lineages within primary tumors. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2140-5.

Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao ZM, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Ann Oncol. 2016 Sep 29. pii: mdw436.


[VIEW FULL LIST OF PUBLICATIONS]