Difference between revisions of "Chuang Lab"

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    <p>Our lab works on problems in the fields of computational biology and bioinformatics. We have studied a wide variety of topics in cancer genomics, gene regulation, and molecular evolution, with particular focuses in post-transcriptional regulation and tumor evolution.</p>
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{{banner|direction=right|title=Welcome |section= |section-link=Chuang_Lab|image=clab_banner2.jpg|width=20%|quote=Our lab uses computational and mathematical approaches to investigate the mechanisms that govern cancer cells and their spatial ecosystems. The lab specializes in problems in cancer image analysis, genomics, and evolution.}}
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{{banner|direction=right|title=Research Topics|section=|image=PDXpicture.png |width=15%|quote=The lab uses computational and mathematical approaches to understand cancer cells and their spatial ecosystems. We develop and apply techniques from a variety of disciplines, including deep neural networks, genomic and evolutionary analysis, and biophysical modeling. We are currently focused in: 1) Multiplex and histopathological cancer image analysis using deep learning, and 2) Cancer evolution in response to therapy.}}
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{{banner|direction=left|title = Publications | section= [https://link.springer.com/article/10.1038/s41467-023-44162-6 Cellos: deconvolution of 3D organoid dynamics at cellular resolution]|image= CellosFig3.jpg|width=45%|quote=}}
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|section = [http://chuanglab.org/News PDXNet U24 grant]
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|quote= The lab has been awarded a National Cancer Institute grant to continue our coordination of data sharing and analysis to general cancer clinical trials for the PDXNet. We are working with institutes including MD Anderson, Dana Farber, Huntsman Cancer Institute, Baylor College of Medicine, the Wistar Institute, Washington University, UC Davis, and Virginia Commonwealth University. For this project we will be analyzing hundreds of new and existing PDX samples toward the goal of developing a clinical trial based on patient-derived xenografts.}}
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<h2><span class="mw-headline" id="Research"><span class="fa fa-news"></span></span> Research</h2>
<p>Prof. Jeffrey Chuang <br>
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<p>Topics that the Chuang Lab investigates
The Jackson Laboratory for Genomic Medicine <br>
 
10 Discovery Drive <br>
 
Farmington, CT 06032 <br>
 
jeff (dot) chuang (at) jax (dot) org
 
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Administrative assistant: Julie Yarmolovich <br>
 
julie (dot) yarmolovich (at) jax (dot) org<br>
 
 
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<h2><span class="mw-headline" id="Features.3F"><span class="fa fa"></span></span> Features</h2>
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<p>Student/postdoctoral/research scientist openings in cancer computational biology.
 
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<h2>Contact Info</h2>
 
Prof. Jeffrey Chuang <br>
 
The Jackson Laboratory for Genomic Medicine <br>
 
10 Discovery Drive <br>
 
Farmington, CT 06032 <br>
 
jeff (dot) chuang (at) jax (dot) org
 
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Administrative assistant: Julie Yarmolovich <br>
 
julie (dot) yarmolovich (at) jax (dot) org<br>
 
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[[Openings]]
 
==Openings==
 
 
Our lab is always open to new students and postdocs excited to work on computational biology problems here at the Jackson Laboratory for Genomic Medicine. We are a computational biology lab specializing in cancer genomics, post-transcriptional regulation and molecular evolution. Our lab works closely with a number of experimental labs to analyze and interpret high-throughput functional genomic data from human and mouse model systems.
 
 
At the post-doctoral level, well-suited candidates should have Ph.D. experience in computational biology, applied math, physics, computer science, or a similar quantitative discipline. Outstanding applicants new to computational biology will also be considered. Strong computing (programming, large scale data analysis, statistical inference, etc), publication, and communication skills are essential. At the graduate student level, a variety of backgrounds can fit, but enthusiasm and aptitude for computational biology are what define the lab.
 
 
Hirees will be joining the Jackson Laboratory for Genomic Medicine, a research institute dedicated to improving human health through genomic approaches. We moved into our newly constructed building and lab space in October 2014. The institute is in Farmington, CT adjacent to the University of Connecticut Medical School and in the Hartford metropolitan area. This institute is part of a $1.1 billion new venture between the Jackson Laboratory (based in Bar Harbor, ME), which is one of the world's leaders in mouse genetics, and the state of Connecticut. JAX Genomic Medicine is building an institute of 30 scientific research groups in the next few years, one third of which are expected to be in computational biology. New hirees will have the opportunity to join one of the first computational biology labs in the institute. Hartford is a lively metropolitan area of over one million people and is within a two hour drive of both Boston and New York City.
 
 
 
Interested applicants should send a CV and a research statement to Jeffrey Chuang at jeff.chuang@jax.org. Reference letters will be requested subsequently.
 
 
Jackson Lab website: http://www.jax.org/
 
Bioscience in Connecticut website: http://biosciencect.uchc.edu/jackson_laboratory/index.html
 
 
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Latest revision as of 11:12, 30 August 2024

Welcome

Our lab uses computational and mathematical approaches to investigate the mechanisms that govern cancer cells and their spatial ecosystems. The lab specializes in problems in cancer image analysis, genomics, and evolution.

Research Topics

The lab uses computational and mathematical approaches to understand cancer cells and their spatial ecosystems. We develop and apply techniques from a variety of disciplines, including deep neural networks, genomic and evolutionary analysis, and biophysical modeling. We are currently focused in: 1) Multiplex and histopathological cancer image analysis using deep learning, and 2) Cancer evolution in response to therapy.

People

Meet the members of the Chuang lab

PDXNet U24 grant

News

The lab has been awarded a National Cancer Institute grant to continue our coordination of data sharing and analysis to general cancer clinical trials for the PDXNet. We are working with institutes including MD Anderson, Dana Farber, Huntsman Cancer Institute, Baylor College of Medicine, the Wistar Institute, Washington University, UC Davis, and Virginia Commonwealth University. For this project we will be analyzing hundreds of new and existing PDX samples toward the goal of developing a clinical trial based on patient-derived xenografts.

Research

Topics that the Chuang Lab investigates

News

Get updated with the current and past news of the Chuang Lab

Openings

Student/postdoctoral/research scientist openings in cancer computational biology.